Hi franz159, does your DAC use a XMOS chip as USB receiver? I gave a quick look on the LH Labs website but I couldn't find any specs about it.
The problem might occur when switching between different sample rates, like in
this case reported by user will. This could depend on custom firmwares that sometimes don't play well with some kernel versions. USB audio world is everything but exact science
We had a similiar problem with some C-Media implementations too, and we developed a dirty workaround for it. You can enable it under the Settings screen and see if it helps in your case.