mo86 wroteI solved the Problem.
Seems the
automatic assigned ip-adress (192.168.2.199) from router suddenly had no connection to internet somehow.
Move to another ip-address was the solution,
the change from DHCP to static ip-mode without changing the ip-adress didn't help...
Don't know why, but it runs for now.

As with all servers (printers, web sites, FTP, SSH, and Raspberry Pi) that need to be found on the network you need to assign a static IP address, you can't always rely on the domain name alone (
http://runeaudio or
http://runeaudio.local), use a static IP address and then the domain name will always point to the correct static assigned IP address. The DHCP server inside your router needs time to update when a new IP address has been assigned to a domain name.
Static IP addresses are not always assigned to the same network devices, it depends if other network devices connect to the network, they may be assigned the IP address that was previously assigned to the Raspberry Pi causing conflicts. If you had problems connecting to the Internet, then that is a router or ISP issue... unless there was some restrictions applied to a specific IP address (inside your router), then all network devices on the network in the same IP range as the router should be able to connect to the Internet. If the router can not connect to the Internet, then nothing else on the network will be able to either.
PS: You
"solved the Problem" but you
"Don't know why" ... I can only conclude this be user error. Sorry.