GAP wroteI'm up and running perfectly with my RPi3. However, since I played around switching between ethernet and wifi my andriod phone have had troubles connecting to runeaudio.local/, both through the app and via any browser. On all other connected devices (desktop, ipad, macbook) it connects flawlessly. Thus I suspect that there is nothing strange going on the the RUNE but with my Andriod. It seems like there is some IP-confusion in my android as connecting through IP.
So the APP has the wrong IP address configured. runeaudio.local is a domain name, this should resolve to an IP address using the DNS (Domain Name Service) in your router. Go to the settings in the APP and change the IP address. The Pi should always have a static IP addressed configure in it... if you use dynamic IP address in the Pi you will continue to have this problem. I just use a browser with the Pi's IP address, bypassing the domain name (runeaudio.local). If you can't find the settings section i the APP, then delete it and reinstall it again... but you will still need to set a static IP address in the Pi.
I'm using the RuneAudio APP in my phone, not android.