Well, I've found this myself

:
Unlike jffs2 and logfs, f2fs is not targeted at raw flash devices, but rather at the specific hardware that is commonly available to consumers — SSDs, eMMC, SD cards, and other flash storage with an FTL (flash translation layer) already built in. It seems that as hardware gets smarter, we need to make even more clever software to manage that "smartness". Does this sound like parenting to anyone else?
http://lwn.net/Articles/518988/
EDIT:
Der Vogel wroteSecondly, as a user of the Raspberry Pi version of RuneAudio, I tried to format the root file system of RuneAudio with F2FS, following
this tutorial. F2FS is "
the new file system designed by Samsung [which] improves the performance and durability of flash memories".
While reading the beginning of the article it seems to me that F2FS improves the performance, but not the durability of SD/eMMC memories, e.g. it does no wear levelling (which is left to the controller).
Seems like a "nice to have" but nothing that is really needed in Runeaudio so far